Monitoring Ovarian Cancer


HE4 is a secreted protein that is over expressed and can be detected in high levels in women with ovarian cancer.  The test is CE-marked for determination of HE4 in human serum for the monitoring of recurrent or progressive disease in patients with epithelial ovarian cancer and for use in combination with CA125 for the determination of risk of EOC in women with a pelvic mass.

Add HE4 to CA125 to Better Monitor Ovarian Cancer

  • HE4 increases by 25% or greater in 60% of patients with disease3
  • HE4 remains constant in 75% of patients without progression of disease3
  • May be used in conjunction with CA125 to monitor epithelial ovarian cancer1,3


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